Advances in sequencing technology have revolutionized our ability to define the genetic components of human health and disease, and the accumulating data continue to refine our understanding of the mechanisms underlying both complex and Mendelian disorders. It is becoming increasingly clear that diseases previously thought of as uniform disorders, including cancer and many psychiatric diseases, vary significantly from patient to patient and that the heritability of disorders is influenced by epigenetics and the environment. In light of these complexities, genomic research and testing are central to advancing personalized medicine.
Themes:
- Cancer genomics
- Psychiatric and neurodegenerative diseases
- Pharmacogenomics
- RNA and disease
- Embryonic development and transgenerational inheritance
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